AmplideX® PCR/CE FMR1

AmplideX PCR/CE FMR1 Reagents are market-leading research tools for the detection of CGG repeats in the fragile X mental retardation (FMR1) gene. These reagents provide a PCR-only approach based on Triplet Repeat Primed PCR (TP-PCR) design to reliably amplify and detect all alleles including Full Mutations.

Features & Benefits

AmplideX PCR/CE FMR1 Reagents* have created an easy-to-use, accessible, high performance method for laboratories to reliably analyze CGG repeats and detect interrupting AGG sequences in the FMR1 gene.

Reduced Complexity
Ease-of-analysis of the FMR1 gene has been simplified through:

Implementation of proprietary PCR solution for amplifying GC-rich regions
Automation of result calling using AmplideX PCR/CE FMR1 Reporter*

Optimized Workflow
Valuable operator hands-on time has been significantly reduced through:

Direct injection of PCR products (no PCR clean up) in to Capillary Electrophoresis platforms
Decreased need for Southern blot analysis (up to 50 fold)
End-to-end solution for FMR1 analysis including all necessary reagents and software

Quality Performance
Performing FMR1 Analysis with Greater Sensitivity and Accuracy:

Detection of all allele expansions, including low abundance full mutation size mosaics with up to at least 1300 CGG repeats
Up to 875 fold more sensitive than Southern blot1
Resolution of female homozygous and heterozygous samples and indication of interrupting AGG sequences
Proven performance as indicated by more than 30 peer reviewed publications

To get the price of AmplideX® mPCR FMR1 and professional advice in selection of equipment, please, contact our consultants in any way convenient for you.